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SACEMA Quarterly update on epidemilogy
Issue 1 March 2009
 IN THIS ISSUE
Editorial
Lancet reports: Carraguard not effective in prevention of HIV
The problem of TB reinfection - an opportunity
Universal Testing and Immediate ART
Short items
 
 ABOUT THIS MAGAZINE
SACEMA Quarterly is an online magazine produced by SACEMA. The aim is to provide regular updates, articles and reviews of developments in quantitative epidemiology. The intention of the magazine is to present this work in a way that it will be accessible to the lay-person and to the interested health professional and policy-maker.
 
 CONTENT CREDITS
Published by:
SACEMA
Editors:
John Hargrove, SACEMA
Alex Welte, SACEMA
Annette A.M Gerritsen, Epi Result
Contributers:
Dr. Brian G. Williams
Dr. Pieter W. Uys
 
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Editorial

Prof. J. Hargrove
It gives me great pleasure to introduce to you the first issue of a Quarterly Magazine produced by SACEMA – the DST/NRF Centre of Excellence in Epidemiological Modelling and Analysis. It is our aim to provide regular updates, articles and reviews of developments in the world of quantitative epidemiology – with particular reference to the human health in the South African scene and to advances in the fight against the twin scourges of HIV and TB.

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Lancet reports: Carraguard not effective in prevention of HIV

Dr. Annette A.M. Gerritsen
Recently the Lancet published the results of a randomized controlled trial which failed to show the effectiveness of the vaginal microbidide gel Carraguard to protect women from becoming HIV infected. This article extensively describes the study methods and results. Furthermore, it reports on ongoing trials on microbicides similair to Carraguard, and those on microbicides that contain antiretroviral drugs (new generation).

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The problem of TB reinfection - an opportunity

Dr. Pieter W. Uys
A significant contributing factor to the high incidence rates of tuberculosis (TB) in countries such as South Africa is the phenomenon of reinfection leading to further disease episodes. Researchers of SACEMA explored the relationship between incidence of TB and reinfection further by constructing a model that simulates the epidemiology of a TB endemic. This article describes the results of this analysis and recommendations based on these.

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Universal Testing and Immediate ART

Dr. Brian G. Williams
The Lancet recently reported that universal HIV testing and immediate antiretroviral therapy (ART) for everyone diagnosed with HIV in countries such as South Africa could reduce new infections by 95% within ten years. This article describes the benefits and objections (costs, human resources, side effects, drug resistance) to the idea of starting all HIV positives on ART in South Africa, including the way forward.

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Short items

Dr. Annette A.M. Gerritsen
Here we present short articles on recent publications, conference announcements and reports related to the work of SACEMA.
  • Highlights from CROI
  • Estimating the lost benefits of antiretroviral drug use in South Africa.
  • Fighting HIV/AIDS, Tuberculosis and Malaria: One World, One Partnership
Read more


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